Volume 4, Issue 1 (Winter 2023)
J Vessel Circ 2023, 4(1): 7-14 |
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Ethics code: IR.MUQ.REC.1400.112
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Movahedi Z, Hajian H, Vahedian M, Nouriyani S, Mosleh M, Khoshgoftar M et al . Investigating Hematology and Laboratory Indicators in Children With Suspected and Confirmed COVID-19. J Vessel Circ 2023; 4 (1) :7-14
URL: http://jvessels.muq.ac.ir/article-1-249-en.html
URL: http://jvessels.muq.ac.ir/article-1-249-en.html
Investigating Hematology and Laboratory Indicators in Children With Suspected and Confirmed COVID-19
Zahra Movahedi1 
, Hanieh Hajian1 , Mostafa Vahedian2 , Shima Nouriyani3 , Mahnaz Mosleh4 , Morteza Khoshgoftar1 , Mohamad Amin Mohabatdost * 5
, Hanieh Hajian1 , Mostafa Vahedian2 , Shima Nouriyani3 , Mahnaz Mosleh4 , Morteza Khoshgoftar1 , Mohamad Amin Mohabatdost * 5
1- Department of Pediatrics, School of Medicine, Hazrat-e Fateme Masoume Hospital, Qom University of Medical Sciences, Qom, Iran
2- Department of Family and Community Medicine, Spiritual Health Research Center, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
3- Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
4- Department of Nursing, School of Nursing and Midwifery, Iranshahr University of Medical Sciences, Iranshahr, Iran.
5- Department of Neurosurgery, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
2- Department of Family and Community Medicine, Spiritual Health Research Center, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
3- Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
4- Department of Nursing, School of Nursing and Midwifery, Iranshahr University of Medical Sciences, Iranshahr, Iran.
5- Department of Neurosurgery, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Abstract: (470 Views)
Background and Aim: It is necessary to evaluate the ability to accurately distinguish cases of pneumonia caused by COVID-19 from other cases of pneumonia in blood parameters. Accordingly, this study evaluates the ability of routine laboratory tests to differentiate pneumonia caused by COVID-19 in patients with suspected and confirmed COVID-19.
Materials and Methods: This was a cross-sectional analytical study, and the information of all patients whose COVID-19 tests were positive or were suspected of this disease and met the inclusion criteria was recorded. The laboratory findings were compared between children with suspected and confirmed COVID-19. The data were analyzed using the SPSS software, version 26. The significant level for all tests was considered P<0.05.
Results: The mean age of the patients was 6.16±3.94 years. A total of 56(46.7%) children were boys, and 64(53.3%) were girls. A statistically significant difference was observed between the two groups regarding the number of white blood cells (P=0.021), the number of lymphocytes (P=0.000), erythrocyte sedimentation rate (P=0.021), C-reactive protein (P=0.023), and D-dimer (P=0.012). However, a statistical difference was observed between the two groups regarding the amount of hemoglobin (P=0.413), platelet (P=0.813), blood urea nitrogen (P=0.299), creatinine (P=0.541), sodium (P=0.265), potassium (P=0.973), lactate dehydrogenase (P=0.275), aspartate aminotransferase (P=0.722), alanine aminotransferase (P=0.699), albumin (P=0.341), prothrombin time (P=0.834), partial thromboplastin time (P=0.499), trop (P=0.121), and ferritin (P=0.233).
Conclusion: The result showed that the inflammatory values of erythrocyte sedimentation rate and C-reactive protein are high in children with confirmed COVID-19. Leukopenia and lymphopenia were also observed in these patients. These results in children with the complaint of COVID-19 lead us to the fastest possible diagnosis and early treatment in these patients.
Materials and Methods: This was a cross-sectional analytical study, and the information of all patients whose COVID-19 tests were positive or were suspected of this disease and met the inclusion criteria was recorded. The laboratory findings were compared between children with suspected and confirmed COVID-19. The data were analyzed using the SPSS software, version 26. The significant level for all tests was considered P<0.05.
Results: The mean age of the patients was 6.16±3.94 years. A total of 56(46.7%) children were boys, and 64(53.3%) were girls. A statistically significant difference was observed between the two groups regarding the number of white blood cells (P=0.021), the number of lymphocytes (P=0.000), erythrocyte sedimentation rate (P=0.021), C-reactive protein (P=0.023), and D-dimer (P=0.012). However, a statistical difference was observed between the two groups regarding the amount of hemoglobin (P=0.413), platelet (P=0.813), blood urea nitrogen (P=0.299), creatinine (P=0.541), sodium (P=0.265), potassium (P=0.973), lactate dehydrogenase (P=0.275), aspartate aminotransferase (P=0.722), alanine aminotransferase (P=0.699), albumin (P=0.341), prothrombin time (P=0.834), partial thromboplastin time (P=0.499), trop (P=0.121), and ferritin (P=0.233).
Conclusion: The result showed that the inflammatory values of erythrocyte sedimentation rate and C-reactive protein are high in children with confirmed COVID-19. Leukopenia and lymphopenia were also observed in these patients. These results in children with the complaint of COVID-19 lead us to the fastest possible diagnosis and early treatment in these patients.
Type of Study: Research |
Subject:
hematology
Received: 2023/02/24 | Accepted: 2023/04/29 | Published: 2024/01/2
Received: 2023/02/24 | Accepted: 2023/04/29 | Published: 2024/01/2
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