Volume 2, Issue 2 (Spring 2021)
J Vessel Circ 2021, 2(2): 77-84 |
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Ebadi Fard Azar F, Sheikh Gholami S, Rezapour A. Epidemiology and Risk Factors of Patients with Acute Coronary Syndrome. J Vessel Circ 2021; 2 (2) :77-84
URL: http://jvessels.muq.ac.ir/article-1-95-en.html
URL: http://jvessels.muq.ac.ir/article-1-95-en.html
1- Health Promotion Research Center, Iran University of Medical Sciences, Tehran, Iran., School of Health Management and Information Sciences, No. 6, Rashid Yasemi St. Vali –e Asr Ave, Tehran, Iran.
2- Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran, School of Health Management and Information Sciences, No. 6, Rashid Yasemi St. Vali –e Asr Ave, Tehran, Iran.
3- Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran, , Tehran, Iran.
2- Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran, School of Health Management and Information Sciences, No. 6, Rashid Yasemi St. Vali –e Asr Ave, Tehran, Iran.
3- Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran, , Tehran, Iran.
Abstract: (1316 Views)
Background and Aim: Cardiovascular disease (CVD) is the most important cause of death worldwide. The incidence and outcome of risk factors differ by type of acute coronary syndrome (ACS). The aim of the present study was to determine the epidemiology and risk factors of patients with ACS in Iran.
Materials and Methods: This is a cross-sectional descriptive study, which was conducted at the Heart Center Hospital, Iran on patients presenting with ACS for a period of one year. An interviewer collected data using an administered data collection form, and epidemiological patterns and risk factors were analyzed by SPSS. One-way analysis of variance (ANOVA) and Chi-square test were used to analyze the hypothesized patterns.
Results: The sample included 710 patients diagnosed with ACS, with Mean±SD age of 60.4±10.27 years, of whom 509 cases (71%) were men and 201 cases (29%) were women. Regarding the type of ACS, 51% of patients were diagnosed with unstable angina (UA), 22% with non-ST elevation myocardial infarction (NSTEMI), and 27% with ST-elevation myocardial infarction (STEMI). Nearly, 37% of cases with STEMI diagnosis, 22.6% with NSTEMI diagnosis, and 16.3% with UA diagnosis were smokers, which indicates a significant association between smoking and STEMI diagnosis (P=0.003). According to the body mass index, a large percentage of the patients were overweight (49%) and only 20.7% had normal body weight. Almost 60% of cases with UA diagnosis, 57% with NSTEMI diagnosis, and 50.5% with STEMI diagnosis had hypertension (HT) (P=0.455), indicating no significant association between hypertension and UA, NSTEMI, and STEMI. About 59% of patients with NSTEMI, 53.2% of patients with UA, and 52% of patients with STEMI had dyslipidemia (P=0.569), indicating no significant association between dyslipidemia and UA, NSTEMI, and STEMI. About 40% of cases with NSTEMI, 37% with STEMI, and 33% with UA diagnosis had diabetes mellitus (P=0.508), indicating no significant association between diabetes mellitus and UA, NSTEMI, and STEMI.
Conclusion: Regarding the occurrence and effect of risk factors, there are three types of ACS. It is necessary to plan to enhance the health level of these patients. Therefore, patients with ACS need special attention in order to be identified and treated as soon as possible.
Materials and Methods: This is a cross-sectional descriptive study, which was conducted at the Heart Center Hospital, Iran on patients presenting with ACS for a period of one year. An interviewer collected data using an administered data collection form, and epidemiological patterns and risk factors were analyzed by SPSS. One-way analysis of variance (ANOVA) and Chi-square test were used to analyze the hypothesized patterns.
Results: The sample included 710 patients diagnosed with ACS, with Mean±SD age of 60.4±10.27 years, of whom 509 cases (71%) were men and 201 cases (29%) were women. Regarding the type of ACS, 51% of patients were diagnosed with unstable angina (UA), 22% with non-ST elevation myocardial infarction (NSTEMI), and 27% with ST-elevation myocardial infarction (STEMI). Nearly, 37% of cases with STEMI diagnosis, 22.6% with NSTEMI diagnosis, and 16.3% with UA diagnosis were smokers, which indicates a significant association between smoking and STEMI diagnosis (P=0.003). According to the body mass index, a large percentage of the patients were overweight (49%) and only 20.7% had normal body weight. Almost 60% of cases with UA diagnosis, 57% with NSTEMI diagnosis, and 50.5% with STEMI diagnosis had hypertension (HT) (P=0.455), indicating no significant association between hypertension and UA, NSTEMI, and STEMI. About 59% of patients with NSTEMI, 53.2% of patients with UA, and 52% of patients with STEMI had dyslipidemia (P=0.569), indicating no significant association between dyslipidemia and UA, NSTEMI, and STEMI. About 40% of cases with NSTEMI, 37% with STEMI, and 33% with UA diagnosis had diabetes mellitus (P=0.508), indicating no significant association between diabetes mellitus and UA, NSTEMI, and STEMI.
Conclusion: Regarding the occurrence and effect of risk factors, there are three types of ACS. It is necessary to plan to enhance the health level of these patients. Therefore, patients with ACS need special attention in order to be identified and treated as soon as possible.
Keywords: Cardiovascular disease, Acute coronary syndrome, Non-ST, elevation myocardial infarction, ST-elevation myocardial, infarction, Angina, Unstable
Type of Study: Research |
Subject:
cardiovascular diseases
Received: 2021/06/30 | Accepted: 2021/09/4 | Published: 2021/07/1
Received: 2021/06/30 | Accepted: 2021/09/4 | Published: 2021/07/1
References
1. Dehghani M, Eshraghi A, Shakeri M, Fallah Rastgar A, Hoshmand G. [Influence of various factors on response to streptokinase therapy for acute myocardial infarction (Persian)]. Medical Journal Of Mashhad University Of Medical Sciences. 2011; 54 (2):113-9. [DOI:10.22038/mjms.2011.5354]
2. Adavi A, Fathi Marghmalaki R, Madmoli Y, Fathi Marghmalaki R, Madmoli M. [the effect of stress management on anxiety of females with hypertension (Persian)]. IJNR. 2016; 11 (5):7-12. [DOI:10.21859/ijnr-11052] [DOI:10.21859/ijnr-11052]
3. Madmoli M, Eilami O, Rezaie K, Aliabad MA, Moslemirad M. [Diabetes and the risk of suffering cardiovascular diseases: A two-year retrospective study (Persian)]. IJEES. 2018; 8 (3):649-56v. [DOI:10.31407/ijees] [DOI:10.31407/ijees]
4. WHO. Noncommunicable diseases: Mortality [Internet]. World Health Organisation. 2016. https://www.who.int/data/gho/data/themes/topics/topic-details/GHO/ncd-mortality
5. Gholami SS, Azar FEF, Rezapour A, Tajdini M. [Cost-effectiveness of coronary artery bypass graft and percutaneous coronary intervention compared to medical therapy in patients with coronary artery disease: A systematic review (Persian)]. Heart Fail Rev. 2019; 24 (6):967-75. [DOI:10.1007/s10741-019-09811-3][PMID]. [DOI:10.1007/s10741-019-09811-3]
6. Majidi S, Moghadam nia M, Sharifi M. [Comparison of signs and symptoms associated with acute coronary syndrome in male and female patients (Persian)]. Jour of gums. 2012; 20 (80):60-6. http://journal.gums.ac.ir/article-1-120-en.html
7. McCaig LF, Burt CW. National hospital ambulatory medical care survey: 2001 emergency department summary. Adv Data. 2003; (335):1-29. [PMID]
8. Hamm CW, Bertrand M, Braunwald E. Acute coronary syndrome without ST elevation: Implementation of new guidelines. Lancet. 2001; 358 (9292):1533-8. [DOI:10.1016/S0140-6736 (01)06585-0][PMID] [DOI:10.1016/S0140-6736(01)06585-0]
9. Sharifirad G, Mohebbi S, Matlabi M. [The relationship of physical activity in middle age and cardiovascular problems in old age in retired people in Isfahan, 2006 (Persian)]. Horizon Med Sci. 2007; 13 (2):57-63. http://hms.gmu.ac.ir/article-1-167-en.html
10. Talaei M, Sarrafzadegan N, Sadeghi M, Oveisgharan S, Marshall T, Thomas GN, et al. [Incidence of cardiovascular diseases in an Iranian population: The Isfahan cohort study (Persian)]. Arch Iran Med. 2013; 16 (3):138-44. [PMID]
11. Ikeda A, Iso H, Toyoshima H, Fujino Y, Mizoue T, Yoshimura T, et al. Marital status and mortality among Japanese men and women: The Japan collaborative cohort study. BMC Public Health. 2007; 7:73. [DOI:10.1186/1471-2458-7-73][PMID][PMCID] [DOI:10.1186/1471-2458-7-73]
12. Panthee B, Kritpracha C. Review: Anxiety and quality of life in patients with myocardial infarction. Nurse Media Journal of Nursing. 2011; 1 (1):105-15. [DOI:10.14710/nmjn.v1i1.750] https://ejournal.undip.ac.id/index.php/medianers/article/view/750
13. Hughes LO, Raval U, Raftery EB. First myocardial infarctions in Asian and white men. BMJ. 1989; 298 (6684):1345-50. [DOI:10.1136/bmj.298.6684.1345][PMID] [PMCID] [DOI:10.1136/bmj.298.6684.1345]
14. Ghaffar A, Reddy KS, Singhi M. Burden of non-communicable diseases in South Asia. BMJ. 2004; 328 (7443):807-10. [DOI:10.1136/bmj.328.7443.807][PMID] [PMCID] [DOI:10.1136/bmj.328.7443.807]
15. Bozkurt B, Hershberger RE, Butler J, Grady KL, Heidenreich PA, Isler ML, et al. 2021 ACC/AHA key data elements and definitions for heart failure: A report of the American college of cardiology/American heart association task force on clinical data standards (writing committee to develop clinical data standards for heart failure). J Am Coll Cardiol. 2021; 77 (16):2053-150. [DOI:10.1016/j.jacc.2020.11.012] [PMID] [DOI:10.1016/j.jacc.2020.11.012]
16. Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth universal definition of myocardial infarction (2018). European Heart Journal. 2019; 40 (3):237-69. [DOI:10.1093/eurheartj/ehy462] https://academic.oup.com/eurheartj/article/40/3/237/5079081#
17. Longmore M, Wilkinson I, Baldwin A, Wallin E. Oxford handbook of clinical medicine-mini edition. OUP Oxford; 2014. https://books.google.com/books/about/Oxford_Handbook_of_Clinical_Medicine.html?id=-tDQAgAAQBAJ [DOI:10.1093/med/9780199609628.001.0001]
18. Ahmadi A, Soori H, Sajjadi H. [Modeling of in hospital mortality determinants in myocardial infarction patients, with and without type 2 diabetes, undergoing pharmaco-invasive strategy: The first national report using two approaches in Iran (Persian)]. Diabetes Res Clin Pract. 2015; 108 (2):216-22. [DOI:10.1016/j.diabres.2015.02.018][PMID] [DOI:10.1016/j.diabres.2015.02.018]
19. Pedigo A, Aldrich T, Odoi A. Neighborhood disparities in stroke and myocardial infarction mortality: A gis and spatial scan statistics approach. BMC Public Health. 2011; 11:644. [DOI:10.1186/1471-2458-11-644][PMID] [PMCID] [DOI:10.1186/1471-2458-11-644]
20. Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, et al. 2011 writing group members; ACCF/AHA task force members. 2011 ACCF/AHA focused update incorporated into the ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-st-elevation myocardial infarction: A report of the American college of cardiology foundation/American heart association task force on practice guidelines. Circulation. 2011; 123 (18):e426-579. [DOI:10.1161/CIR.0b013e318212bb8b][PMID] [DOI:10.1161/CIR.0b013e318212bb8b]
21. Amsterdam EA, Wenger NK, Brindis RG, Casey DE Jr, Ganiats TG, Holmes DR Jr, et al. 2014 AHA/ACC guideline for the management of patients with non-st-elevation acute coronary syndromes: A report of the American college of cardiology/american heart association task force on practice guidelines. J Am Coll Cardiol. 2014; 64 (24):e139-e228. [DOI:10.1016/j.jacc.2014.09.017][PMID] [DOI:10.1016/j.jacc.2014.09.017]
22. Mohanan PP, Mathew R, Harikrishnan S, Krishnan MN, Zachariah G, Joseph J, et al. Kerala ACS Registry Investigators. Presentation, management, and outcomes of 25 748 acute coronary syndrome admissions in Kerala, India: Results from the Kerala acs registry. Eur Heart J. 2013; 34 (2):121-9. [DOI:10.1093/eurheartj/ehs219][PMID] [PMCID] [DOI:10.1093/eurheartj/ehs219]
23. Medagama A, Bandara R, De Silva C, Galgomuwa MP. Management of acute coronary syndromes in a developing country; Time for a paradigm shift? an observational study. BMC Cardiovasc Disord. 2015; 15:133. [DOI:10.1186/s12872-015-0125-y][PMID] [PMCID] [DOI:10.1186/s12872-015-0125-y]
24. Ralapanawa U, Kumarasiri PVR, Jayawickreme KP, Kumarihamy P, Wijeratne Y, Ekanayake M, et al. Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka. BMC Cardiovasc Disord. 2019; 19 (1):229. [DOI:10.1186/s12872-019-1217-x][PMID] [PMCID] [DOI:10.1186/s12872-019-1217-x]
25. Mashali H, Toleideh F, Rahmani R, Darabiyan P, Madmoli M. [The predictive role of hyperlipidemia in the incidence of ACS in patients referring to Shahidzadeh hospital in Behbahan in 2016-2017 (Persian)]. Medical Science. 2018; 22 (94):566-70. http://discoveryjournals.org/medicalscience/current_issue/v22/n94/index.htm
26. Azar FEF, Solhi M, Chabaksvar F. [Investigation of the quality of life of patients with hypertension in health centers (Persian)]. J Educ Health Promot. 2020; 9:185. [DOI:10.4103/jehp.jehp_741_19][PMID] [PMCID] [DOI:10.4103/jehp.jehp_741_19]
27. Gholami SS, Azar FEF, Rezapour A, Tajdini M. [Cost-effectiveness of coronary artery bypass graft and percutaneous coronary intervention compared to medical therapy in patients with coronary artery disease: A systematic review (Persian)]. Heart Fail Rev. 2019; 24 (6):967-75. [DOI:10.1007/s10741-019-09811-3] [PMID] [DOI:10.1007/s10741-019-09811-3]
28. ACCESS Investigators. Management of acute coronary syndromes in developing countries: Acute coronary events-a multinational survey of current management strategies. Am Heart J. 2011; 162 (5):852-59.e22. [DOI:10.1016/j.ahj.2011.07.029][PMID] [DOI:10.1016/j.ahj.2011.07.029]
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