Volume 2, Issue 1 (Winter 2021)                   J Vessel Circ 2021, 2(1): 9-16 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ramezani S, Biniaz S A, Yaqoubi M, Akbarpor Beni M. The Effect of Muscle Endurance Training on Blood Pressure, Resting Heart Rate and Endothelin-1 Levels in Inactive Men. J Vessel Circ 2021; 2 (1) :9-16
URL: http://jvessels.muq.ac.ir/article-1-76-en.html
1- Department of Physical Education and Sports Science, Faculty of Sports Sciences, Arak University, Arak, Iran., sajjad_ramezanii@yahoo.com
2- Department of Physical Education and Sports Sciences, Qazvin Branch, Islamic Azad University, Qazvin, Iran., abbas.biniaz1351@gmail.com
3- Department of Sports Science, Faculty of Literature and Humanities, Lorestan University, Khorramabad, Iran., mohsen.yaqoubi@gmail.com
4- Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Qom University, Qom, Iran., akbarpour.mohsen@gmail.com
Abstract:   (1347 Views)
Background and Aim: Sports activities play a protective and preventive role against heart diseases by reducing their risk factors. This study aimed to evaluate the effect of resistance training by muscle endurance method on blood pressure, heart rate, and plasma endothelin-1 levels of inactive healthy men.
Materials and Methods: In this quasi-experimental study, 30 middle-aged men (Mean±SD age: 47.03±2.12 years, Mean±SD height: 172.90±3 cm, Mean±SD weight: 80.70±3.1 kg, Mean±SD Body Mass Index: 27.47±3.66 kg/m², and Mean±SD waist to hip ratio: 0.98 0±1.27) were purposefully selected and then randomly divided into the control and experimental groups (each 15 members). The experimental group performed 8 weeks of resistance training, three sessions per week with an intensity of 40% to 70% of 1 repetition maximum. Plasma endothelin-1, systolic and diastolic blood pressure, and resting heart rate were measured before and after 8 weeks of exercise. The dependent t-test was used to examine intra-group changes, and the independent t-test was used for inter-group differences. The significance level was considered less than 0.05.
Results: Eight weeks of muscular endurance resistance training significantly reduced endothelin-1 plasma levels of inactive middle-aged men (P=0.002). Also, 8 weeks of resistance training significantly reduced their systolic blood pressure (P=0.001) and resting heart rate (P=0.01), but the decrease in diastolic blood pressure was not significant (P=0.0411).
Conclusion: Based on the present study results, muscular endurance resistance training as a preventive factor can decrease the risk of hypertension and heart disease in healthy middle-aged men by reducing plasma endothelin-1 levels, systolic blood pressure, and resting heart rate.
Full-Text [PDF 891 kb]   (457 Downloads) |   |   Full-Text (HTML)  (624 Views)  
Type of Study: Research | Subject: cardiovascular diseases
Received: 2021/05/24 | Accepted: 2021/06/19 | Published: 2021/03/30

References
1. [1] Hedayati R, Mahmoodi S, Bagheri R, Biglary M, Bakhtiary AH, Mirmohammadkhani M. Effect of different types of lower-limb exercise on blood pressure in hypertensive people: A randomized, double-blind controlled clinical trial. Middle East J Rehabil Health Stud. 2021; 8(1):e106789. [DOI:10.5812/mejrh.106789] [DOI:10.5812/mejrh.106789]
2. [2] Hakimi M, Ali-Mohammadi M, Baghaiee B, Siahkouhian M, Bolboli L. [Comparing the effects of 12-weeks of resistance and endurance training on ANP, endothelin-1, apelin and blood pressure in hypertensive middle-aged men (Persian)]. Stud Med Sci. 2016; 26(12):1080-9. http://umj.umsu.ac.ir/article-1-3291-fa.html
3. [3] Zhang X, Li Y, Del Gobbo LC, Rosanoff A, Wang J, Zhang W, et al. Effects of magnesium supplementation on blood pressure: A meta-analysis of randomized double-blind placebo-controlled trials. Hypertension. 2016; 68(2):324-33.[DOI:10.1161/HYPERTENSIONAHA.116.07664] [PMID] [DOI:10.1161/HYPERTENSIONAHA.116.07664]
4. [4] Ramezani S, Parasteah M, Zohrehvandian K. [The effect of resistance training on plasma levels of endothelin 1 and blood pressure in older men (Persian)]. J North Khorasan Univ Med Sci. 2020; 12(3):31-9. http://journal.nkums.ac.ir/article-1-2149-en.html
5. [5] Ghassemian A, Salesi M. [The effect of an 8-week concurrent training on plasma endothelin_1 level and blood pressure of old women (Persian)]. J Kerman Univ Med Sci. 2014; 20(1):11-24. http://jkmu.kmu.ac.ir/article_16465.html
6. [6] Davenport AP, Hyndman KA, Dhaun N, Southan C, Kohan DE, Pollock JS, et al. Endothelin. Pharmacol Rev. 2016; 68(2):357-418.[DOI:10.1124/pr.115.011833] [PMID] [PMCID] [DOI:10.1124/pr.115.011833]
7. [7] Faramarzi M, Azamiyan Jozi A, Ghasemiyan A. [The effect of resistance exercise on endothelin-1 conecntation, systolic and diastolic blood pressure of older women (Persian)]. Appl Res Sport Manage. 2012; 1(1):95-104. http://arsmb.journals.pnu.ac.ir/article_236.html?lang=en
8. [8] Nor Arfuzir NN, Agarwal R, Iezhitsa I, Agarwal P, Ismail NM. Magnesium acetyltaurate protects against endothelin-1 induced RGC loss by reducing neuroinflammation in Sprague dawley rats. Exp Eye Res. 2020; 194:107996. [DOI:10.1016/j.exer.2020.107996] [PMID] [DOI:10.1016/j.exer.2020.107996]
9. [9] Koller B, Steringer-Mascherbauer R, Ebner CH, Weber Th, Ammer M, Eichinger J, et al. Pilot study of endothelin receptor blockade in heart failure with diastolic dysfunction and pulmonary hypertension (BADDHY-Trial). Heart Lung Circ. 2017; 26(5):433- 41. [DOI:10.1016/j.hlc.2016.09.004] [PMID] [DOI:10.1016/j.hlc.2016.09.004]
10. [10] Mankar SM, Jagia GJ, Shenvi D, Kaurani VG. Comparison of physical fitness index and maximal aerobic capacity pre and post stair case climbing. Int J Physiol. 2018; 6(3):54-9. [DOI:10.5958/2320-608X.2018.00085.9] [DOI:10.5958/2320-608X.2018.00085.9]
11. [11] Afshar Jafari A, Saeidi S, Zekri R, Malekirad A. [Comparison of static and dynamic resistance exercise effects on some functional cardiovascular indices, plasma lactate and peripheral blood leukocytes in healthy untrained women (Persian)]. J Shahrekord Uuniv Med Sci. 2012; 14(1):66-76. https://www.sid.ir/fa/journal/ViewPaper.aspx?ID=158085
12. [12] Arazi H, Pahlevanzadeh M, Afkhami Ardekani M. [Effect of single bout aerobic and resistance exercise on the pain perception and cardiovascular responses in women with Multiple Sclerosis (Persian)]. J Inflamm Dis. 2016; 20(5):42-34. http://journal.qums.ac.ir/article-1-2167-en.html
13. [13] Maeda S, Miyauchi T, Iemitsu M, Sugawara J, Nagata Y, Goto K. Resistance exercise training reduces plasma endothelin-1 concentration in healthy young humans. J Cardiovasc Pharmacol. 2004; 44 Suppl 1:S443-6.[DOI:10.1097/01.fjc.0000166319.91623.b0] [PMID] [DOI:10.1097/01.fjc.0000166319.91623.b0]
14. [14] Maeda S, Jesmin S, Iemitsu M, Otsuki T, Matsuo T, Ohkawara K, et al. Weight loss reduces plasma endothelin-1 concentration in obese men. Exp Biol Med (Maywood). 2006; 231(6):1044-7. [PMID]
15. [15] Sardeli AV. [arterial compliance afer resistance exercise protocols in elderly (Portuguese)] [Msc. thesis]. Campinas: UNICAMP Universidade Estadual de Campinas; 2015. http://repositorio. unicamp.br/jspui/handle/REPOSIP/321363
16. [16] Boroujerdi SS, Rahimi R, Noori SR. Effect of high-versus lowintensity resistance training on post-exercise hypotension in male athletes. Int SportMed J. 2009; 10(2):95-100. https://hdl. handle.net/10520/EJC48371
17. [17] Gibson AL, Wagner DR, Heyward VH. Advanced fitness assessment and exercise prescription. Champaign: Human Kinetics; 2018. https://books.google.com/books?id=FjxnDwAAQBAJ&dq
18. [18] Rezaeimanesh D. The Effect of a 12-week regular aquatic exercise on plasma levels of nitric oxide, endothelin-1, and some platelet indices in healthy young men. J Advance Pharmacy Educ Res. 2020; 10(S1):114-9. https://www.researchgate.net/publication/339586285_The_Effect_of_a_12-Week_Regular_Aquatic_Exercise_on_Plasma_Levels_of_Nitric_Oxide_Endothelin-1_and_some_Platelet_Indices_in_Healthy_Young_Men
19. [19] Ballard KD, Timsina R, Timmerman KL. Influence of time of day and intermittent aerobic exercise on vascular endothelial function and plasma endothelin-1 in healthy adults. Chronobiol Int. 2021; 38(7):1064-71. [DOI:10.1080/07420528.2021.1907395] [PMID] [DOI:10.1080/07420528.2021.1907395]
20. [20] Nakamura N, Muraoka I. Effects of vigorous resistance training on cardiovagal baroreflex sensitivity: A cross-sectional study. 2021. [DOI:10.21203/rs.3.rs-378443/v1] [DOI:10.21203/rs.3.rs-378443/v1]
21. [21] Kazemzadeh Y, Sadegian S, Mohammadnejad Panah Kandi Y. [The response of plasma endothelin and nitric oxide to a session of aerobic exercise with blood flow restriction in active girls (Persian)]. Sport Physiol Manag Invest. 2020; 12(3):175-85. http://www.sportrc.ir/article_122536.html?lang=en
22. [22] Tagawa K, Ra SG, Kumagai H, Yoshikawa T, Yoshida Y, Takekoshi K, et al. Effects of resistance training on arterial compliance and plasma endothelin-1 levels in healthy men. Physiol Res. 2018;67(Suppl 1):S155-66. [DOI:10.33549/physiolres.933818] [PMID] [DOI:10.33549/physiolres.933818]
23. [23] Rahnama N, Nouri R, Rahmaninia F, Damirchi A, Emami H. The effects of exercise training on maximum aerobic capacity, resting heart rate, blood pressure and anthropometric variables of postmenopausal women with breast cancer. J Res Med Sci. 2010; 15(2):78-83. [PMID] [PMCID]
24. [24] Mortimer J, Mckune AJ. Effect of short-term isometric handgrip training on blood pressure in middle-aged females. Cardiovasc J Afr. 2011; 22(5):257-60. [DOI:10.5830/CVJA-2010-090] [PMID] [PMCID] [DOI:10.5830/CVJA-2010-090]
25. [25] Hidari H, Bolurchifard F, Yaghmaei F, Naseri N, Hamadzadeh S. [The effect of short-term aerobic exercise on the blood pressure in elderly clients with hypertension (Persian)]. Med Surg Nurs J. 2014; 3(1):45-51. https://sites.kowsarpub.com/msnj/articles/87735.html
26. [26] Figueroa A, Okamoto T, Jaime SJ, Fahs CA. Impact of high-and low-intensity resistance training on arterial stiffness and blood pressure in adults across the lifespan: A review. Pflugers Arch. 2019; 471(3):467-78. [DOI:10.1007/s00424-018-2235-8] [PMID] [DOI:10.1007/s00424-018-2235-8]
27. [27] Godinho MR. Health and work conditions and their influence on work ability-a prospective cohort study with public university employees (Portuguese)]. Rio de Janeiro: Oswaldo Cruz Foundation; 2017. https://www.arca.fiocruz.br/handle/icict/24111
28. [28] Arazi H, Afkhami M. Effects of acute resistance exercise on blood pressure and pain threshold in type 2 diabetic overweight patients. J Knowl Health. 2013; 8(2):57-61. [DOI:10.22100/jkh.v8i2.25]
29. [29] Atif M, Saleem Q, Babar ZUD, Scahill S. Association between the vicious cycle of diabetes-associated complications and glycemic control among the elderly: A systematic review. Medicina (Kaunas). 2018; 54(5):73. [DOI:10.3390/medicina54050073] [PMID] [PMCID] [DOI:10.3390/medicina54050073]
30. [30] Mokhtari M, Daryanosh F. [The effect of 11 weeks of resistance exercise on plasma levels of Aplin-11 Nesfatin-1 and resting heart rate in elderly women with hypertension (Persian)]. Med J Mashhad Univ Med Sci. 2015; 58(6):330-7. [DOI:10.22038/MJMS.2015.5002]
31. [31] Eghbali F, Moradi M. [The effect of a course of pilates exercise on hypertension, nitric oxide, and resting heart rate in the eldrly men with hypertension (Persian)]. J Arak Med Sci. 2017;19(11):1-10. http://jams.arakmu.ac.ir/article-1-4176-en.html
32. [32] Franklin SS, Gustin 4th W, Wong ND, Larson MG, Weber MA, Kannel WB, et al. Hemodynamic patterns of age-related changes in blood pressure: The Framingham heart study. Circulation. 1997; 96(1):308-15. [DOI:10.1161/01.CIR.96.1.308] [PMID] [DOI:10.1161/01.CIR.96.1.308]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2025 CC BY-NC 4.0 | Journal of Vessels and Circulation

Designed & Developed by : Yektaweb