Volume 5, Issue 2 (Spring 2024)
J Vessel Circ 2024, 5(2): 0-0 |
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Ghafari R, Tork Zadeh A, Aminzadeh A, Roshanzamir I, Taraz Jamshidi S. Evaluation of Apoptosis Evidence in Oral Mucosa of Patients Undergoing CT Scan. J Vessel Circ 2024; 5 (2)
URL: http://jvessels.muq.ac.ir/article-1-297-en.html
URL: http://jvessels.muq.ac.ir/article-1-297-en.html
Roshanak Ghafari * 
1, Azade Tork Zadeh1 , Atousa Aminzadeh1 , Imaneh Roshanzamir1 , Saeede Taraz Jamshidi1
1, Azade Tork Zadeh1 , Atousa Aminzadeh1 , Imaneh Roshanzamir1 , Saeede Taraz Jamshidi1
1- Associate professor
Abstract: (73 Views)
Computed Tomography (CT) scanning is a widely used diagnostic technique in medical imaging, particularly in the head and neck region. Although it provides high-resolution images, concerns remain about the potential cytotoxic and genotoxic effects of ionizing radiation. This study aimed to assess the impact of CT scan radiation on the epithelial cells of the oral mucosa, including the buccal, gingival, and lingual regions. Cytological samples were collected before and after CT scan exposure using a cytobrush, and cellular damage was analyzed using the Papanicolaou (Pap) staining method. The slides were assessed by a pathologist for each cellular parameter, recording abnormalities per 1000 cells. The results revealed a significant increase in nuclear abnormalities such as micronuclei, pyknosis, nuclear budding, and binucleated cells, especially in the gingival mucosa. Statistical analysis indicated significant differences between pre- and post-exposure samples (p < 0.05). This study underscores the cytotoxic and genotoxic risks associated with CT scans and highlights the need for careful consideration of radiation exposure, particularly in the head and neck region.
Type of Study: Research |
Subject:
interventional vascular radiology
Received: 2025/01/26 | Accepted: 2025/02/5 | Published: 2024/12/31
Received: 2025/01/26 | Accepted: 2025/02/5 | Published: 2024/12/31
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