Volume 5, Issue 2 (Spring 2024)
J Vessel Circ 2024, 5(2): 0-0 |
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Ethics code: IR.MUQ.REC.1403.107
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Farasat E, modarresi mosalla Z, habibi najafi N. A case of secondary pseudohypoaldosteronism that presented with severe dehydration and tachycardia and hypotention. J Vessel Circ 2024; 5 (2)
URL: http://jvessels.muq.ac.ir/article-1-292-en.html
URL: http://jvessels.muq.ac.ir/article-1-292-en.html
1- PEDIATRIC CLINICAL RESEARCH DEVELOPMENT UNIT,HAZRAT MASOUMEH HOSPITAL.QOM UNIVERSITY OF MEDICAL SCIENCES.QOM.IRAN, QOM.HAZRAT MASOUMEH HOSPITAL
2- PEDIATRIC CLINICAL RESEARCH DEVELOPMENT UNIT,HAZRAT MASOUMEH HOSPITAL.QOM UNIVERSITY OF MEDICAL SCIENCES.QOM.IRAN, QOM. HAZRAT MASOUMEH HOSPITAL
2- PEDIATRIC CLINICAL RESEARCH DEVELOPMENT UNIT,HAZRAT MASOUMEH HOSPITAL.QOM UNIVERSITY OF MEDICAL SCIENCES.QOM.IRAN, QOM. HAZRAT MASOUMEH HOSPITAL
Abstract: (99 Views)
Introduction: Secondary pseudohypoaldosteronism (PHA) is a rare condition characterized by resistance to the action of aldosterone, leading to disturbances in electrolyte balance, particularly hyperkalemia and hyponatremia. It can arise from various underlying issues including renal tubular immaturity and urinary tract anomalies. In this case we reported of Secondary Pseudohypoaldosteronism Presenting with Severe Dehydration, Tachycardia, and Hypotension
Case Presentation: A 27-day-old male infant presented with dehydration, hyponatremia, hyperkalemia, and metabolic acidosis. Investigations revealed elevated aldosterone and cortisol, a urinary tract infection (UTI), and severe bilateral vesicoureteral reflux (VUR) with hydronephrosis. He was treated with fluids, electrolytes, antibiotics, and steroids. At 6 months, he was doing well on steroid replacement and UTI prophylaxis, awaiting surgery for VUR. The case suggests secondary pseudohyperaldosteronism likely secondary to the severe UTI and VUR.
Conclusion: In newborns and infants, secondary hyperaldosteronism (PHA) can lead to hyponatremia and hyperkalemia, conditions diagnosed using imaging techniques. The condition is linked to underdeveloped kidneys, urinary tract malformations, and infections, but its precise mechanisms and etiology remain areas requiring further investigation.
Case Presentation: A 27-day-old male infant presented with dehydration, hyponatremia, hyperkalemia, and metabolic acidosis. Investigations revealed elevated aldosterone and cortisol, a urinary tract infection (UTI), and severe bilateral vesicoureteral reflux (VUR) with hydronephrosis. He was treated with fluids, electrolytes, antibiotics, and steroids. At 6 months, he was doing well on steroid replacement and UTI prophylaxis, awaiting surgery for VUR. The case suggests secondary pseudohyperaldosteronism likely secondary to the severe UTI and VUR.
Conclusion: In newborns and infants, secondary hyperaldosteronism (PHA) can lead to hyponatremia and hyperkalemia, conditions diagnosed using imaging techniques. The condition is linked to underdeveloped kidneys, urinary tract malformations, and infections, but its precise mechanisms and etiology remain areas requiring further investigation.
Keywords: pseudohypoaldosteronism (PHA)type1, urinary tract infection, vesicourethral reflux, secondary PHA
Type of Study: case report |
Subject:
vascular nephrology
Received: 2024/11/12 | Accepted: 2025/02/4 | Published: 2024/12/31
Received: 2024/11/12 | Accepted: 2025/02/4 | Published: 2024/12/31
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