Volume 5, Issue 2 (Spring 2024)
J Vessel Circ 2024, 5(2): 0-0 |
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Armanian A M, Ghasemian M, Babakhanian M, Barekatain B, Seyedebrahimi R. Evaluation of serum zinc level in neonatal umbilical cord vessels and its relation with neonatal outcomes. J Vessel Circ 2024; 5 (2)
URL: http://jvessels.muq.ac.ir/article-1-279-en.html
URL: http://jvessels.muq.ac.ir/article-1-279-en.html
Amir Mohammad Armanian 
, Mina Ghasemian , Masoudeh Babakhanian , Behzad Barekatain , Reihaneh Seyedebrahimi * 1
, Mina Ghasemian , Masoudeh Babakhanian , Behzad Barekatain , Reihaneh Seyedebrahimi * 1
Abstract: (81 Views)
Background: Maternal mineral levels play a critical role in the growth of the fetus during pregnancy. Zinc is an important nutrient that its deficiency may be associated with poor outcomes in infants. This study evaluated the relationship of serum zinc concentration of the umbilical cord blood with the infant’s different parameters in groups of preterm and term infants.
Materials & Methods: Six hundred newborns divided to two groups according to gestational age in term (> 35 W) and preterm (< 35 W). Umbilical cord blood samples were collected and the zinc levels were analyzed using Atomic Absorption Spectroscopy (AAS) with flame atomization. The zinc levels were compared between groups and the effect of zinc levels with different neonatal and maternal evaluated.
Results: Our data indicated that levels of zinc have significant adverse correlations with birth weight and Apgar score in neonates regardless of gestational age (P < 0.05). In late preterm and term infants whose mothers are diabetics, zinc levels of the umbilical cord were low compared with normal mothers (P < 0.05). Also, zinc levels had significant adverse relationships with RDS and asphyxia in preterm neonate (P < 0.05). In both groups, lower zinc levels were reported in the mothers who had received corticosteroids (P < 0.05).
Conclusion: The study demonstrates a significant relationship between umbilical cord zinc levels and neonatal outcomes, particularly in preterm infants. However, these findings should be interpreted with caution due to potential confounding factors such as maternal health conditions, socioeconomic influences, and measurement limitations.
Materials & Methods: Six hundred newborns divided to two groups according to gestational age in term (> 35 W) and preterm (< 35 W). Umbilical cord blood samples were collected and the zinc levels were analyzed using Atomic Absorption Spectroscopy (AAS) with flame atomization. The zinc levels were compared between groups and the effect of zinc levels with different neonatal and maternal evaluated.
Results: Our data indicated that levels of zinc have significant adverse correlations with birth weight and Apgar score in neonates regardless of gestational age (P < 0.05). In late preterm and term infants whose mothers are diabetics, zinc levels of the umbilical cord were low compared with normal mothers (P < 0.05). Also, zinc levels had significant adverse relationships with RDS and asphyxia in preterm neonate (P < 0.05). In both groups, lower zinc levels were reported in the mothers who had received corticosteroids (P < 0.05).
Conclusion: The study demonstrates a significant relationship between umbilical cord zinc levels and neonatal outcomes, particularly in preterm infants. However, these findings should be interpreted with caution due to potential confounding factors such as maternal health conditions, socioeconomic influences, and measurement limitations.
Type of Study: Research |
Subject:
vascular physiology
Received: 2024/06/18 | Accepted: 2025/01/20 | Published: 2024/12/31
Received: 2024/06/18 | Accepted: 2025/01/20 | Published: 2024/12/31
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