Volume 4, Issue 2 (Spring 2023)
J Vessel Circ 2023, 4(2): 75-82 |
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Research code: IR.MUQ.REC.1399.146
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Movahedi Z, Heydari H, Vahedian M, Hajian H, Noori A, Hosseini R et al . Serological Findings of Children With COVID-19 and Clinical and Paraclinical Results. J Vessel Circ 2023; 4 (2) :75-82
URL: http://jvessels.muq.ac.ir/article-1-264-en.html
URL: http://jvessels.muq.ac.ir/article-1-264-en.html
Zahra Movahedi1 
, Hosein Heydari1 , Mostafa Vahedian2 , Hanieh Hajian1 , Azadeh Noori * 1, Reihanehsadat Hosseini3 , Simin Noori4
, Hosein Heydari1 , Mostafa Vahedian2 , Hanieh Hajian1 , Azadeh Noori * 1, Reihanehsadat Hosseini3 , Simin Noori4
1- Department of Pediatrics, School of Medicine, Hazrat-e Fateme Masoume Hospital, Qom University of Medical Sciences, Qom, Iran.
2- Department of Family and Community Medicine, Spiritual Health Research Center, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
3- School of Medicine, University of Virginia, Charlottesville, United States.
4- Department of Pediatrics, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
2- Department of Family and Community Medicine, Spiritual Health Research Center, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
3- School of Medicine, University of Virginia, Charlottesville, United States.
4- Department of Pediatrics, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Abstract: (554 Views)
Background and Aim: This research aims to examine the serological outcomes of pediatric patients with COVID-19 and their correlation with the clinical and paraclinical outcomes of children hospitalized at Hazrat Masoumeh Hospital in the mid-year of 2021.
Materials and Methods: The study collected data from a database of patients who were definitively diagnosed with COVID-19. The study also recorded the clinical outcomes of these patients (such as discharge, death, and length of hospitalization) for one month after their hospitalization, which was the last day of follow-up. Information on epidemiological, clinical, laboratory data, radiological indicators, treatment, and clinical consequences was extracted from the patient’s electronic medical records using data collection forms. All the gathered information was then entered into SPSS software, version 22 and analyzed using statistical tests. The significance level for all tests was set at 0.05.
Results: No significant relationship was observed between the immunoglobulin (Ig) M response and any of the clinical symptoms (P>0.05). The IgG response was statistically significantly related only to diarrhea and abdominal pain among the clinical symptoms experienced by patients (P<0.05). Among laboratory symptoms, thrombocytopenia had a statistically significant relationship with IgM (P=0.009), and positive urine culture had a statistically significant relationship with IgG (P=0.00). Other laboratory symptoms had no statistically significant relationship with serological findings (P>0.05). Imaging results had a statistically significant relationship only with Ig G (P=0.00) and no significant statistical relationship with IgM (P=0.23).
Conclusion: The study results indicate that the serological results of these patients are also significant for diagnosing this disease.
Materials and Methods: The study collected data from a database of patients who were definitively diagnosed with COVID-19. The study also recorded the clinical outcomes of these patients (such as discharge, death, and length of hospitalization) for one month after their hospitalization, which was the last day of follow-up. Information on epidemiological, clinical, laboratory data, radiological indicators, treatment, and clinical consequences was extracted from the patient’s electronic medical records using data collection forms. All the gathered information was then entered into SPSS software, version 22 and analyzed using statistical tests. The significance level for all tests was set at 0.05.
Results: No significant relationship was observed between the immunoglobulin (Ig) M response and any of the clinical symptoms (P>0.05). The IgG response was statistically significantly related only to diarrhea and abdominal pain among the clinical symptoms experienced by patients (P<0.05). Among laboratory symptoms, thrombocytopenia had a statistically significant relationship with IgM (P=0.009), and positive urine culture had a statistically significant relationship with IgG (P=0.00). Other laboratory symptoms had no statistically significant relationship with serological findings (P>0.05). Imaging results had a statistically significant relationship only with Ig G (P=0.00) and no significant statistical relationship with IgM (P=0.23).
Conclusion: The study results indicate that the serological results of these patients are also significant for diagnosing this disease.
Keywords: COVID-19, Serology, Child, Severe-acute-respiratory-syndrome-related coronavirus, Coronavirus
Type of Study: Research |
Subject:
hematology
Received: 2023/10/16 | Accepted: 2023/12/5 | Published: 2024/02/29
Received: 2023/10/16 | Accepted: 2023/12/5 | Published: 2024/02/29
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