Volume 3, Issue 4 (Autumn 2022)
J Vessel Circ 2022, 3(4): 159-164 |
Back to browse issues page
Ethics code: IR.MUQ.REC.1399.203
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Arjmandnia M H, Minae N, Vahedian M, Tafaroji J, Yousefi M, Mirmohammadi H S, et al . The Frequency of Single Umbilical Artery in Fetal Ultrasound Among Neonates With Congenital Heart Disease Compared to Neonates Without Congenital Heart Disease. J Vessel Circ 2022; 3 (4) :159-164
URL: http://jvessels.muq.ac.ir/article-1-243-en.html
URL: http://jvessels.muq.ac.ir/article-1-243-en.html
Mohammad Hossein Arjmandnia1 
, Neda Minae1 , Mostafa Vahedian2 , Javad Tafaroji3 , Maryam Yousefi4 , Hamideh Sadat Mirmohammadi * 3, Mohammad Hassan Tavazo1 , Milad Siamaki1
, Neda Minae1 , Mostafa Vahedian2 , Javad Tafaroji3 , Maryam Yousefi4 , Hamideh Sadat Mirmohammadi * 3, Mohammad Hassan Tavazo1 , Milad Siamaki1
1- Department of Pediatrics, School of Medicine, Hazrat-e Fatemeh Masoumeh Hospital, Qom University of Medical Sciences, Qom, Iran.
2- Department of Family and Community Medicine, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
3- Department of Pediatrics, School of Medicine, Hazrat-e Fatemeh Masoumeh Hospital, Qom University of Medical Sciences, Qom, Iran
4- Department of Obstetrics and Gynecology, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
2- Department of Family and Community Medicine, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
3- Department of Pediatrics, School of Medicine, Hazrat-e Fatemeh Masoumeh Hospital, Qom University of Medical Sciences, Qom, Iran
4- Department of Obstetrics and Gynecology, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
Abstract: (450 Views)
Background and Aim: The need for more fetal echocardiography by a specialist in isolated single umbilical artery (SUA) pregnancies is controversial. Therefore, this study aimed to investigate the frequency of SUA in fetal ultrasound in neonates with congenital heart disease (CHD) compared to neonates without CHD referred to Hazrat Masoumeh Hospital in 2019.
Materials and Methods: The files of all the neonates who underwent fetal ultrasound and echocardiography in 2019 were reviewed. Based on the results of the fetal echocardiography, these neonates were divided into two groups with/without cardiac abnormalities. Then, the results of fetal ultrasound performed in terms of the frequency of SUA were examined in the groups, and variables, such as birth, weight, gestational age, and gender were entered into the checklist. Finally, the frequency of SUA in fetuses with/without cardiac abnormalities was compared between the two groups.
Results: The mean age of mothers in the SUA group was 32.47±8.7 years and in the normal group was 32.07±11.5 years. A total of 135 boys (54%) and 115 girls (46%) were examined in this study. No statistically significant relationship was found between maternal age (P=0.72), fetal gender (P=0.92), gestational age (P=0.42), and parity (P=0.92) despite the finding of a SUA. In the group of patients with CHD, 12 out of 125 patients (4.8%), and in the group without CHD, five out of 125 patients (2%) had an SUA. Although this number was highest in the group who had CHD, no statistically significant difference was found between the two groups (0.07).
Conclusion: The relationship between SUA in a fetus with normal ultrasound and CHD varies significantly with population selection criteria. The risk of CHD after diagnosing SUA in a normal fetus from an unselected population appears to be low and may not warrant specialized fetal echocardiography.
Materials and Methods: The files of all the neonates who underwent fetal ultrasound and echocardiography in 2019 were reviewed. Based on the results of the fetal echocardiography, these neonates were divided into two groups with/without cardiac abnormalities. Then, the results of fetal ultrasound performed in terms of the frequency of SUA were examined in the groups, and variables, such as birth, weight, gestational age, and gender were entered into the checklist. Finally, the frequency of SUA in fetuses with/without cardiac abnormalities was compared between the two groups.
Results: The mean age of mothers in the SUA group was 32.47±8.7 years and in the normal group was 32.07±11.5 years. A total of 135 boys (54%) and 115 girls (46%) were examined in this study. No statistically significant relationship was found between maternal age (P=0.72), fetal gender (P=0.92), gestational age (P=0.42), and parity (P=0.92) despite the finding of a SUA. In the group of patients with CHD, 12 out of 125 patients (4.8%), and in the group without CHD, five out of 125 patients (2%) had an SUA. Although this number was highest in the group who had CHD, no statistically significant difference was found between the two groups (0.07).
Conclusion: The relationship between SUA in a fetus with normal ultrasound and CHD varies significantly with population selection criteria. The risk of CHD after diagnosing SUA in a normal fetus from an unselected population appears to be low and may not warrant specialized fetal echocardiography.
Type of Study: Research |
Subject:
interventional vascular radiology
Received: 2023/01/16 | Accepted: 2023/03/18 | Published: 2023/05/31
Received: 2023/01/16 | Accepted: 2023/03/18 | Published: 2023/05/31
References
1. Thummala MR, Raju TN, Langenberg P. Isolated single umbilical artery anomaly and the risk for congenital malformations: A meta-analysis. J Pediatr Surg. 1998; 33(4):580-5. [DOI:10.1016/S0022-3468(98)90320-7] [PMID] [DOI:10.1016/S0022-3468(98)90320-7]
2. Sun HY. Prenatal diagnosis of congenital heart defects: Echocardiography. Transl Pediatr. 2021; 10(8):2210-24. [Link] [DOI:10.21037/tp-20-164]
3. DeFigueiredo D, Dagklis T, Zidere V, Allan L, Nicolaides KH. Isolated single umbilical artery: Need for specialist fetal echocardiography? Ultrasound Obstet Gynecol. 2010; 36(5):553-5. [DOI:10.1002/uog.7711] [PMID] [DOI:10.1002/uog.7711]
4. Kim HJ, Kim JH, Chay DB, Park JH, Kim MA. Association of isolated single umbilical artery with perinatal outcomes: Systemic review and meta-analysis. Obstet Gynecol Sci. 2017; 60(3):266-73. [DOI:10.5468/ogs.2017.60.3.266] [PMID] [PMCID] [DOI:10.5468/ogs.2017.60.3.266]
5. Lubusky M, Dhaifalah I, Prochazka M, Hyjanek J, Mickova I, Vomackova K, et al. Single umbilical artery and its siding in the second trimester of pregnancy: Relation to chromosomal defects. Prenat Diagn. 2007; 27(4):327-31. [PMID][DOI:10.1002/pd.1672] [DOI:10.1002/pd.1672]
6. Herrmann Jr UJ, Sidiropoulos D. Single umbilical artery: Prenatal findings. Prenat Diagn. 1988; 8(4):275-80. [DOI:10.1002/pd.1970080405] [PMID] [DOI:10.1002/pd.1970080405]
7. Hill LM, Wibner D, Gonzales P, Chenevey P. Validity of transabdominal sonography in the detection of a two-vessel umbilical cord. Obstet Gynecol. 2001; 98(5 Pt 1):837-42. [DOI:10.1016/S0029-7844(01)01572-1] [PMID] [DOI:10.1016/S0029-7844(01)01572-1]
8. Granese R, Coco C, Jeanty P. The value of single umbilical artery in the prediction of fetal aneuploidy: Findings in 12,672 pregnant women. Ultrasound Q. 2007; 23(2):117-21.[DOI:10.1097/01.ruq.0000263848.07808.02] [PMID] [DOI:10.1097/01.ruq.0000263848.07808.02]
9. Friedberg MK, Silverman NH. Changing indications for fetal echocardiography in a university center population. Prenat Diagn. 2004; 24(10):781-6. [DOI:10.1002/pd.981] [PMID] [DOI:10.1002/pd.981]
10. Araujo Júnior E, Palma-Dias R, Martins WP, Reidy K, da Silva Costa F. Congenital heart disease and adverse perinatal outcome in fetuses with confirmed isolated single functioning umbilical artery. J Obstet Gynaecol. 2015; 35(1):85-7. [DOI:10.3109/01443615.2014.935720] [PMID] [DOI:10.3109/01443615.2014.935720]
11. Wang J, Ye Y, Xin T, Zhang X, Chen S, Wu Y, et al. Is echocardiography necessary for all single umbilical artery fetuses? A retrospective study in a selected Chinese population. J Obstet Gynaecol Res. 2019; 45(4):803-9. [DOI:10.1111/jog.13912] [PMID] [DOI:10.1111/jog.13912]
12. Prefumo F, Güven MA, Carvalho JS. Single umbilical artery and congenital heart disease in selected and unselected populations. Ultrasound Obstet Gynecol. 2010; 35(5):552-5. [DOI:10.1002/uog.7642] [PMID] [DOI:10.1002/uog.7642]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Owned by Qom University of Medical Sciences
Published by Qom University of Medical Sciences Press
eISSN: 2717-0357
Email: jvessels[at]muq.ac.ir
j.vessels.circul[at]gmail.com
