Volume 1, Issue 1 (Winter 2020)
J Vessel Circ 2020, 1(1): 33-36 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Arjmandnia M H, Yousefi M, Rezvan S, Vahedian M, Noori E, Mohammadi A, et al . Evaluation of Congenital Heart Diseases in Neonates with Diabetic Mothers Who Referred to Teaching Hospitals in Qom, Iran. J Vessel Circ 2020; 1 (1) :33-36
URL: http://jvessels.muq.ac.ir/article-1-27-en.html
URL: http://jvessels.muq.ac.ir/article-1-27-en.html
Mohammad Hossein Arjmandnia1 
, Maryam Yousefi1 , Sajad Rezvan2 , Mostafa Vahedian3 , Enayatollah Noori * 3, Aboutaleb Mohammadi3 , Akram Barati3 , Fatemeh Sharifi2 , Fatemeh Amirkanian4
, Maryam Yousefi1 , Sajad Rezvan2 , Mostafa Vahedian3 , Enayatollah Noori * 3, Aboutaleb Mohammadi3 , Akram Barati3 , Fatemeh Sharifi2 , Fatemeh Amirkanian4
1- Qom University of Medical Sciences, Qom, Iran
2- Rafsanjan University of Medical Sciences
3- Qom University of Medical Sciences
4- Department of Research and Technology, Qom University of Medical Sciences
2- Rafsanjan University of Medical Sciences
3- Qom University of Medical Sciences
4- Department of Research and Technology, Qom University of Medical Sciences
Abstract: (1909 Views)
Background and Aim: Neonates of diabetic mothers are more prone to congenital heart diseases than others. These abnormalities are the leading cause of fetal death in diabetic neonates. Therefore, the determination of a screening method and evaluation of its value seems necessary in such neonates. The present study investigated the various types of congenital heart diseases in neonates of diabetic mothers.
Materials and Methods: The present descriptive cross-sectional study evaluated the prevalence of congenital heart malformations on 200 neonates of diabetic mothers who had referred to the teaching hospitals of Qom, Iran. The designed checklists included the maternal age, gestational age, gender of the infant, occupation of the mother, family history, maternal diabetes, Apgar, respiratory distress, cyanosis, and echocardiographic results.
Results: Based on the findings, echocardiographic results of 82 neonates of diabetic mothers were abnormal. Moreover, it was concluded that the infant weight abnormality, reception of oral medications, overt diabetes, and the decrease of fasting blood glucose had a significant relationship with heart diseases in infants of diabetic mothers. Moreover, the study found that echocardiographic results were abnormal in 49% of neonates of diabetic mothers. Furthermore, 3%, 1.5%, 69.5%, 41%, 0%, and 3.5% of the participants had VSD, ASD, PFO, PDA, MR, and TR.
Conclusion: Based on the results, it was concluded that 9 out of each 10 diabetic neonates have congenital heart anomalies, with PFO being the most common one of them.
Materials and Methods: The present descriptive cross-sectional study evaluated the prevalence of congenital heart malformations on 200 neonates of diabetic mothers who had referred to the teaching hospitals of Qom, Iran. The designed checklists included the maternal age, gestational age, gender of the infant, occupation of the mother, family history, maternal diabetes, Apgar, respiratory distress, cyanosis, and echocardiographic results.
Results: Based on the findings, echocardiographic results of 82 neonates of diabetic mothers were abnormal. Moreover, it was concluded that the infant weight abnormality, reception of oral medications, overt diabetes, and the decrease of fasting blood glucose had a significant relationship with heart diseases in infants of diabetic mothers. Moreover, the study found that echocardiographic results were abnormal in 49% of neonates of diabetic mothers. Furthermore, 3%, 1.5%, 69.5%, 41%, 0%, and 3.5% of the participants had VSD, ASD, PFO, PDA, MR, and TR.
Conclusion: Based on the results, it was concluded that 9 out of each 10 diabetic neonates have congenital heart anomalies, with PFO being the most common one of them.
Type of Study: Research |
Subject:
stroke
Received: 2019/11/21 | Accepted: 2020/02/15 | Published: 2020/01/30
Received: 2019/11/21 | Accepted: 2020/02/15 | Published: 2020/01/30
References
1. Nold JL, Georgieff MK.. Infants of diabetic mothers. Pediatr Clin North Am 2004;51(3):619-37. PMID: 15157588 [DOI:10.1016/j.pcl.2004.01.003]
2. Kliegman RM, Behrman RE, Jenson HB, Stanton BM. Nelson textbook of pediatrics e-book. 18th ed. New York: Elsevier Health Sciences; 2016. P. 599-8. Link
3. Correa A, Gilboa SM, Besser LM, Botto LD, Moore CA, Hobbs CA, et al. Diabetes mellitus and birth defects. Am J Obstet Gynecol 2008;199(3):237.e1-9. PMID: 18674752 [DOI:10.1016/j.ajog.2008.06.028]
4. Fanaroff AA, Martin RJ. Neonatal-perinatal medicine: diseases of the fetus and infant. 7th ed. New York: Mosby Elsevier; 2012. P. 1306-4. Link
5. Senanayake MP, Gunawardene MK. Neonatal morbidity following control of maternal diabetes with human insulin. Sri Lanka J Child Health 2000;29:11-4. Link [DOI:10.4038/sljch.v29i1.592]
6. Ornoy A, Reece EA, Pavlinkova G, Kappen C, Miller RK. Effect of maternal diabetes on the embryo, fetus, and children: congenital anomalies, genetic and epigenetic changes and developmental outcomes. Birth Defects Res Part C Embryo Today 2015;105(1):53-72. PMID: 25783684 [DOI:10.1002/bdrc.21090]
7. Lisowski LA, Verheijen PM, Copel JA, Kleinman CS, Wassink S, Visser GH, et al. Congenital heart disease in pregnancies complicated by maternal diabetes mellitus. An international clinical collaboration, literature review, and meta-analysis. Herz 2010;35(1):19-26. PMID: 20140785 [DOI:10.1007/s00059-010-3244-3]
8. Abu-Sulaiman RM, Subaih B. Congenital heart disease in infants of diabetic mothers: echocardiographic study. Pediatr Cardiol 2004;25(2):137-40. PMID: 14648003 [DOI:10.1007/s00246-003-0538-8]
9. Russell NE, Holloway P, Quinn S, Foley M, Kelehan P, McAuliffe FM. Cardiomyopathy and cardiomegaly in stillborn infants of diabetic mothers. Pediatr Dev Pathol 2008; 11(1):10-4. PMID: 18237240 [DOI:10.2350/07-05-0277.1]
10. Moradian M, Tabib A, Ghasempour A, Alaee N, Akbarzadeh Z. Comparing ventricular function in fetuses of diabetic and non-diabetic mothers using tissue doppler imaging. Res Cardiovasc Med 2016;5(4):e31864. Link [DOI:10.5812/cardiovascmed.31864]
11. Chang JK, Jien WY, Chen HL, Hsieh KS. Color Doppler echocardiographic study on the incidence and natural history of early-infancy muscular ventricular septal defect. Pediatr Neonatol 2011;52(5):256-60. PMID: 22036220 [DOI:10.1016/j.pedneo.2011.06.003]
12. Deorari A, Saxena A, Singh M, Shrivastava S. Echocardiographic assessment of infants born to diabetic mothers. Arch Dis Child 1989;64(5):721-4. PMID: 2730127 [DOI:10.1136/adc.64.5.721]
13. Ekici F, Tutar E, Atalay S, Arsan S, Özçelik N. The incidence and follow-up of isolated ventricular septal defect in newborns by echocardiographic screening. Turk J Pediatr 2008;50(3):223-7. PMID: 18773666
14. Vahedian M, Yosefi M, Mohammadi A, Rezvan S, Noori E, Rezaei G, et al. Evaluation of referral indications for fetal echocardiography in pregnant women referred to Echocardiography unit of Masoumeh Hospital in the winter of 2018. Jundishapur Sci Med J 2019;18(4):369-77. Link
15. Arjmandnia M, Besharati M, Rezvan S. Studying the determinant factors leading to congenital heart disease in newborns. J Educ Health Promot 2018;7:53. PMID: 29693034 [DOI:10.4103/jehp.jehp_146_17]
16. Behjati M, Modarresi V, Rahimpour S, Behjati MA. Congenital heart diseases in the newborns of diabetic mothers: an echocardiographic study. J Shahid Sadoughi Univ Med Sci 2011;19(4):511-7. Link
17. Najafian B, Akbari Asbagh P, Shohrati M, Nili F, Nayeri F. Comparison of echocardiographic findings in diabetic and non-diabetic mothers' infants. Kowsar Med J 2006;11(3):267-72. Link
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Owned by Qom University of Medical Sciences
Published by Qom University of Medical Sciences Press
eISSN: 2717-0357
Email: jvessels[at]muq.ac.ir
j.vessels.circul[at]gmail.com
